SkinMedica TNS Advanced+ Serum
SkinMedica's most advanced growth factor serum.
TNS Advanced+ is the brand's hero anti-aging serum, built on its most advanced growth factor technology. It works on two fronts at once: lifting the look of sagging skin and improving firmness, while smoothing the appearance of lines and wrinkles. The dual-chamber bottle keeps both formulas fresh and potent until the moment you use them.
Why it is worth it
This is widely regarded as one of the most powerful topical anti-aging serums available, with the clinical results to back it. It is an investment, but for visible firmness and smoother skin from a single serum, very little compares. One bottle lasts months.
How it compares
For barrier and hydration support alongside it, layer HA5 or TNS Ceramide. For pure resurfacing, add Retinol Complex at night. TNS Advanced+ is the centerpiece a routine builds around.
Best for: anyone serious about firmness, lift, and lines who wants one standout serum.
Not ideal for: very tight budgets, or those wanting a single targeted concern like pigment.
How to use
Apply to clean skin morning and night, before moisturizer.



